100 Results for "

Garcinia paucinervis Chun et How

" in MedChemExpress (MCE) Product Catalog:
Products (100)

100 Results for "Garcinia paucinervis Chun et How" in MCE Product Catalog:

6
6 Publications Verification
Cat. No.: HY-N0087
CAS No.: 2752-65-0
Synonyms: Beta-Guttiferrin
Gambogic Acid (Beta-Guttiferrin) is derived from the gamboges resin of the tree Garcinia hanburyi. Gambogic Acid (Beta-Guttiferrin) inhibits Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1 with IC50s of 1.47 μM, 1.21 μM, 2.02 μM, 0.66 μM, 1.06 μM and 0.79 μM.
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5
5 Cited Publications
Cat. No.: HY-107569
CAS No.: 78824-30-3
Pureté:  ≥99.0%
Garcinol, a polyisoprenylated benzophenone harvested from Garcinia indica, exerts anti-cholinesterase properties towards acetyl cholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50s of 0.66 μM and 7.39 μM, respectively . Garcinol also inhibits histone acetyltransferases (HATs, IC50= 7 μM) and p300/CPB-associated factor (PCAF, IC50 = 5 μM). Garcinol has anti-inflammatory and anti-cancer activity .
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2
2 Cited Publications
Cat. No.: HY-N6954
CAS No.: 76996-27-5
Garcinone C, a xanthone derivative, is a natural compound extracted from Garcinia oblongifolia that is used as an anti-inflammatory, astringency and granulation-promoting medicine, and has potential cytotoxic effects on certain cancers. Garcinone C stimulates the expression levels of ATR and 4E-BP1, arrests the cell cycle, inhibits cell viability of the human Nasopharyngeal carcinoma (NPC) cell lines CNE1, CNE2, HK1 and HONE1 in a time‑ and dose‑dependent manner through inhibition of Hedgehog signaling pathway. Garcinone C is orally active .
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1
1 Cited Publications
Cat. No.: HY-79139
CAS No.: 119-24-4
Target:  

Drug Intermediate

Domaines de recherche:  

Metabolic Disease

Pteroic acid is a precursor to significant compounds like Folic acid (HY-16637) and Vitamin B12 (HY-B0315). Pteroic acid facilitates the examination of how different compounds influence cell growth and development .
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1
1 Cited Publications
Cat. No.: HY-W338584
CAS No.: 232281-44-6
Tripotassium hydroxycitrate is an orally active, multi-target, multi-bioactive organic acid. Tripotassium hydroxycitrate activates Nrf2 and its downstream molecule GPX4, increases glutathione levels, and thereby inhibits ferroptosis. Tripotassium hydroxycitrate activates the Nrf2/Keap1 and ACLY/NF-κB signaling pathways, upregulates the activities of antioxidant enzymes such as superoxide dismutase, reduces MDA content, thereby alleviating oxidative stress and renal tubular epithelial cell apoptosis, and improves pulmonary vascular and right ventricular remodeling. Tripotassium hydroxycitrate activates both the AMPK and mTORC1/S6K pathways, triggers the unfolded protein response, arrests the cancer cell cycle, and induces DNA fragmentation .
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1
1 Cited Publications
Cat. No.: HY-N4094
CAS No.: 5304-71-2
Morellic acid is isolated from Garcinia Morella with an antiangiogenic activity .
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Cat. No.: HY-N3347
CAS No.: 519-34-6
Synonyms: Maclurin
Macurin is a xanthone that can be isolated from Garcinia lancilimba .
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Cat. No.: HY-N7933
CAS No.: 646-31-1
Synonyms: ALKANE C24
Target:  

Apoptosis

Domaines de recherche:  

Inflammation/Immunology

Tetracosane (ALKANE C24) is a natural product that can be found in Acrostichum aureum. Tetracosane hows cytotoxicity and induces Apoptosis. Tetracosane has the potential for the research of peptic ulcer .
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Cat. No.: HY-135712
CAS No.: 1936-15-8
Synonyms: Acid Orange GG
Orange G is an azo dye commonly found in textile wastewater and is mainly used for textile dyeing. Orange G has a coloring function and can give textiles a specific color. The stability and potential hazards of Orange G in the environment are often used to study the removal effects of various wastewater treatment technologies on difficult-to-degrade organic pollutants, especially the degradation of azo dyes. Related research focuses on how to destroy the azo bond of Orange G through chemical, physical or biological methods to achieve harmless treatment to solve the problem of textile wastewater pollution .
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Cat. No.: HY-N7347
CAS No.: 27750-13-6
Synonyms: Garcinia lactone
(-)-Hydroxycitric acid lactone (Garcinia lactone) is an anti-obesity agent and a popular weight loss food supplement. (-)-Hydroxycitric acid lactone is a potent inhibitor of ATP-citrate lyase. (-)-Hydroxycitric acid lactone catalyzes the extramitochondrial cleavage of citrate to oxaloacetate and acetyl-CoA, limits the availability of acetyl-CoA units required for fatty acid synthesis .
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Cat. No.: HY-P10449
CAS No.: 3098205-40-1
Target:  

Peptides

Domaines de recherche:  

Inflammation/Immunology Cancer

M2 Peptide is a peptide targeting M2-like tumor-associated macrophages (TAMs). M2 Peptide is used to carry drugs or small interfering RNA (siRNA) to promote the repolarization of M2-like macrophages to M1-like macrophages, thereby altering the immunosuppressive state in the tumor microenvironment and enhancing the anti-tumor immune response. M2 Peptide can be used to study the effect of macrophage polarization and how this polarization change affects tumor growth and metastasis .
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Cat. No.: HY-N14035
CAS No.: 90045-23-1
Garcinia cambogia extract is an orally active anti-obesity agent . Garcinia cambogia extract upregulates the gene expression of aP2, SREBP1c, PPARγ2 and C/EBPα. Garcinia cambogia extract reduces the rate of body weight gain, visceral fat accumulation, lipid levels in blood and liver, as well as plasma insulin and leptin levels . Garcinia cambogia extract ameliorates high-fat diet-induced obesity .
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Cat. No.: HY-N2795
CAS No.: 35349-68-9
Synonyms: Xanthone I
Target:  

Parasite Bacterial

Domaines de recherche:  

Infection

9-Hydroxycalabaxanthone (Xanthone I) is a known xanthone isolated from Garcinia mangostana Linn. 9-Hydroxycalabaxanthone has quorum-sensing inhibitory, anti-microbial, and anti-malarial activities (IC50=1.2-1.5 μM) .
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Cat. No.: HY-N5115
CAS No.: 54081-47-9
Neosmitilbin is isolated from Garcinia mangostana.
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Cat. No.: HY-N6248
CAS No.: 212842-64-3
Cowaxanthone B is a xanthone isolated from the fruits of Garcinia cowa. Cowaxanthone B has weak antibacterial activity .
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Cat. No.: HY-101546A
CAS No.: 32728-75-9
Synonyms: (+)-Cavidine
Cavidine ((+)-Cavidine) is an analgesic and anti-inflammatory agent. Cavidine can be isolated from Corydalis ternata f. yanhusuo (Y.H.Chou & Chun C.Hsu) Y.C.Zhu. Cavidine reduces the expression of inflammatory factors IL-1β, IL-6 and TNF-α, and inhibits calcium ion influx. Cavidine inhibits the phosphorylation of p38 and ERK1/2. Cavidine increases mechanical and thermal pain thresholds in chronic pain models. Cavidine can be used for the research of chronic pain .
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Cat. No.: HY-N10678
CAS No.: 881027-35-6
R-30-Hydroxygambogic acid is polyprenylated xanthone epimer that can be isolated from gamboges of Garcinia hanburyi. R-30-Hydroxygambogic acid shows cytotoxicities to Human Leukemia K562 cell lines of IC50 values of 2.89 and 1.27 μM for K562/R and K562/S, respectively. R-30-Hydroxygambogic acid can be used for the research of cancer .
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Cat. No.: HY-N9113
CAS No.: 5084-31-1
1,3,5,6-Tetrahydroxyxanthone is a natural xanthone that can be isolated from Garcinia achachairu Rusby (Clusiaceae) branches. 1,3,5,6-Tetrahydroxyxanthone induces diuresis and saluresis in normotensive and hypertensive rats .
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Cat. No.: HY-W100715
CAS No.: 6638-05-7
4-Methylsyringol is a phenolic syringol derivative found in a variety of plants. Phenolic compounds are widely present in food and plants and have high synthetic, medicinal, and industrial value. Polyphenols are compounds with various phenolic functions. Natural polyphenols can regulate the cell cycle, induce apoptosis, inhibit cell adhesion, migration, proliferation, and differentiation, and possess a variety of biological activities such as antioxidation, anti-inflammation, anticancer, and antimutagenic effects .
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Cat. No.: HY-N8876
CAS No.: 1243249-16-2
Paucinervin A (Compound 1) is a type of bittern. Paucinervin A inhibits the growth of HeLa cells (IC50=29.5 μM). Paucinervin A is isolated from the natural Garcinia paucinervis .
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